Rooter Medical
Regenerative Medicine
Wint

Biovico

Wint

WNT pathway modulation through DKK-1

The only technology in the world able to extract DKK-1 from platelets. Wint can halt the progression of osteoarthritis by blocking the WNT pathway, reaching a DKK-1 concentration up to 5.8 times higher than the level found in healthy individuals' plasma.

Indications

  • Osteoarthritis at various stages

Technical specifications

Application
Single annual dose
DKK-1 concentration
Up to 5.8x versus healthy plasma levels

Technology

Wint tube technology

Wint tube with the platelet activator spheres visible inside
  • Integrated platelet activator

    Spheres made from a special borosilicate composition, carrying a permanent electrostatic charge on their surface, which selectively induce the patient's own platelets to secrete high levels of DKK-1.

  • Closed system with pressure equalization

    Blood transfer without removing the stopper, eliminating exposure and reducing contamination risk throughout the process.

  • Very low surface energy

    A property of the Makrolon polycarbonate that minimizes platelet and leukocyte adhesion to the tube's inner wall, resulting in greater cell recovery in the final concentrate.

  • Transverse stabilization rings

    Internal structures that keep the blood column stable during centrifugation, preventing hemolysis and preserving the integrity of the separated fractions.

  • Precision volumetric markings

    Allow the exact volume to be obtained at each separation stage, with strict control over the final dose to be applied.

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