
Biovico
Wint
WNT pathway modulation through DKK-1
The only technology in the world able to extract DKK-1 from platelets. Wint can halt the progression of osteoarthritis by blocking the WNT pathway, reaching a DKK-1 concentration up to 5.8 times higher than the level found in healthy individuals' plasma.
Indications
- Osteoarthritis at various stages
Technical specifications
- Application
- Single annual dose
- DKK-1 concentration
- Up to 5.8x versus healthy plasma levels
Technology
Wint tube technology

Integrated platelet activator
Spheres made from a special borosilicate composition, carrying a permanent electrostatic charge on their surface, which selectively induce the patient's own platelets to secrete high levels of DKK-1.
Closed system with pressure equalization
Blood transfer without removing the stopper, eliminating exposure and reducing contamination risk throughout the process.
Very low surface energy
A property of the Makrolon polycarbonate that minimizes platelet and leukocyte adhesion to the tube's inner wall, resulting in greater cell recovery in the final concentrate.
Transverse stabilization rings
Internal structures that keep the blood column stable during centrifugation, preventing hemolysis and preserving the integrity of the separated fractions.
Precision volumetric markings
Allow the exact volume to be obtained at each separation stage, with strict control over the final dose to be applied.



